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・ Thyroid function tests
・ Thyroid hormone
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・ Thyroid hormone receptor alpha
・ Thyroid hormone receptor beta
・ Thyroid hormone resistance
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Thyroid's secretory capacity
・ Thyroid-hormone transaminase
・ Thyroid-like follicular renal cell carcinoma
・ Thyroid-stimulating hormone
・ Thyroid-stimulating hormone measurement
・ Thyroidectomy
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Thyroid's secretory capacity : ウィキペディア英語版
Thyroid's secretory capacity
Thyroid's secretory capacity (GT, also referred to as thyroid's incretory capacity, maximum thyroid hormone output, T4 output or, if calculated from levels of thyroid hormones, as SPINA-GT) is the maximum stimulated amount of thyroxine that the thyroid can produce in a given time-unit (e.g. one second).
== How to determine GT ==
Experimentally, GT can be determined by stimulating the thyroid with high a thyrotropin concentration and measuring its output in terms of T4 production.
''In vivo'', GT can also be estimated from equilibrium levels of TSH and T4 or free T4. In this case it is calculated with
\hat G_T =
or
\hat G_T =
\hat G_T : Theoretical (apparent) secretory capacity (SPINA-GT)

\alpha _T: Dilution factor for T4 (reciprocal of apparent volume of distribution, 0.1 l−1)

\beta _T: Clearance exponent for T4 (1.1e-6 sec−1)

''K''41: Dissociation constant T4-TBG (2e10 l/mol)

''K''42: Dissociation constant T4-TBPA (2e8 l/mol)

''D''''T'': EC50 for TSH (2.75 mU/l)〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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