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Thyroid's secretory capacity (GT, also referred to as thyroid's incretory capacity, maximum thyroid hormone output, T4 output or, if calculated from levels of thyroid hormones, as SPINA-GT) is the maximum stimulated amount of thyroxine that the thyroid can produce in a given time-unit (e.g. one second). == How to determine GT == Experimentally, GT can be determined by stimulating the thyroid with high a thyrotropin concentration and measuring its output in terms of T4 production. ''In vivo'', GT can also be estimated from equilibrium levels of TSH and T4 or free T4. In this case it is calculated with or : Theoretical (apparent) secretory capacity (SPINA-GT) : Dilution factor for T4 (reciprocal of apparent volume of distribution, 0.1 l−1) : Clearance exponent for T4 (1.1e-6 sec−1) ''K''41: Dissociation constant T4-TBG (2e10 l/mol) ''K''42: Dissociation constant T4-TBPA (2e8 l/mol) ''D''''T'': EC50 for TSH (2.75 mU/l)〔 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Thyroid's secretory capacity」の詳細全文を読む スポンサード リンク
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